Killian C A, Roberge R J, Krenzelok E P, Stonage C L
Department of Emergency Medicine of the Western Pennsylvania Hospital, Pittsburgh, USA.
Pediatr Emerg Care. 1997 Oct;13(5):340-1. doi: 10.1097/00006565-199710000-00011.
We present a case of accidental transdermal clonidine toxicity in a six-year-old child who was applying a clonidine patch intermittently to her dermis in the mistaken assumption that it was an adhesive bandage. Although the child appeared to be drug toxic, she repeatedly denied ingestion of any substances to family, paramedics, and hospital staff but was not initially questioned regarding dermal exposure. In dealing with drug toxic states in which the differential diagnosis includes drugs available as transdermal delivery systems, the evaluation should include questions regarding possible dermal exposure and a thorough skin examination.
我们报告一例6岁儿童意外经皮可乐定中毒病例，该儿童误以为可乐定贴片是创可贴，便间歇性地将其贴在皮肤上。尽管该儿童似乎药物中毒，但她多次向家人、护理人员和医院工作人员否认摄入任何物质，最初却未被问及皮肤接触情况。在处理鉴别诊断包括经皮给药系统可用药物的药物中毒状态时，评估应包括询问可能的皮肤接触情况并进行全面的皮肤检查。
