Rush B R
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Kansas State University, Manhattan, USA.
Vet Clin North Am Equine Pract. 1997 Dec;13(3):531-48. doi: 10.1016/s0749-0739(17)30229-8.
Pharmacologic manipulation of pulmonary immunity plays an important role in primary and adjunct therapy for equine respiratory disease. Frequent exposure to respiratory viral pathogens, strenuous exercise, long distance transport, and inhalation of harmful substances destroy various aspects of the pulmonary defense system and predispose performance horses to development of infectious and noninfectious respiratory disease. Pulmonary immunity may be bolstered by nonspecific immunostimulants to combat primary or secondary immunodeficiency. State of the art technology improves active and passive-specific immunity for prevention of common infectious respiratory diseases in horses. Immuno-suppressive therapy can attenuate hyperreactive pulmonary immune responses in horses with allergic airway disease.
对肺部免疫进行药物调控在马呼吸道疾病的主要治疗和辅助治疗中发挥着重要作用。频繁接触呼吸道病毒病原体、剧烈运动、长途运输以及吸入有害物质会破坏肺部防御系统的各个方面，使竞技马匹易患传染性和非传染性呼吸道疾病。非特异性免疫刺激剂可增强肺部免疫力，以对抗原发性或继发性免疫缺陷。先进技术可提高主动和被动特异性免疫力，预防马常见的传染性呼吸道疾病。免疫抑制疗法可减轻患有过敏性气道疾病马匹的肺部高反应性免疫反应。
