Banderas Tarabay J A, González Begné M
Centro de Investigaciones y Estudios Avanzados de la Facultad de Odontología, Universidad Autónoma del Estado de México, Toluca.
Bol Estud Med Biol. 1996 Jan-Dec;44(1-4):19-23.
Genetic polymorphism is the major contributor that affects human salivary composition. In order to determine the molecular phenotypes in saliva, it is important to know the distribution of proteins with specific functions which allows the clinical diagnosis of specific diseases. Unstimulated human whole saliva samples from 120 subjects were subjected to sodium dodecyl sulfate polyacrylamide slab gel electrophoresis (SDS-PAGE). The phenotype distribution of several molecules including MG1, MG2, alpha-Amylase, PRP-I and cystatins were similar. Qualitative and quantitative characteristics were specific in each subject.
基因多态性是影响人类唾液成分的主要因素。为了确定唾液中的分子表型，了解具有特定功能的蛋白质分布情况很重要，这有助于特定疾病的临床诊断。对120名受试者的非刺激性人类全唾液样本进行了十二烷基硫酸钠聚丙烯酰胺平板凝胶电泳（SDS-PAGE）。包括MG1、MG2、α-淀粉酶、PRP-I和半胱氨酸蛋白酶抑制剂在内的几种分子的表型分布相似。每个受试者的定性和定量特征都是特定的。
