Huot P, Dousset V, Hatier F, Degreze P, Carlier P, Caillé J M
Service de Radiologie, Hopital d'Instruction des Armées Robert Picqué, Route de Toulouse, F-33 998 Bordeaux Armées, France.
Eur Radiol. 1997;7 Suppl 5:174-7. doi: 10.1007/pl00006889.
Magnetization transfer (MT) provides post-gadolinium contrast improvement through decreasing the tissue signal. Our study had two aims: to analyse the effect of MT qualitatively and quantitatively in 13 patients, and to analyse in vitro the competition between two relaxation phenomena, dipole-dipole which is characteristic of MT and proton - electron which is characteristic of gadolinium. Contrast between lesion and white matter improved from 20.6 % before MT to 65.1 % after MT, enabling new lesions to be detected in two patients. The improvement was due mainly to the proton - electron effect of gadolinium rather than the dipole relaxation of MT. These results are in agreement with those in the literature. The existence of spontaneous high-signal induced by MT in the absence of gadolinium indicates that it is preferable to perform an MT sequence before and after administration of gadolinium.
磁化传递（MT）通过降低组织信号来改善钆增强后的对比度。我们的研究有两个目的：定性和定量分析13例患者中MT的效果，以及在体外分析两种弛豫现象之间的竞争，即MT特有的偶极-偶极相互作用和钆特有的质子-电子相互作用。病变与白质之间的对比度从MT前的20.6%提高到MT后的65.1%，使得两名患者中的新病变得以检测到。这种改善主要归因于钆的质子-电子效应，而非MT的偶极弛豫。这些结果与文献中的结果一致。在没有钆的情况下MT诱导的自发高信号的存在表明，最好在给予钆之前和之后进行MT序列检查。
