Bygdeman S, Eliasch H
Acta Med Scand. 1976;199(6):475-9. doi: 10.1111/j.0954-6820.1976.tb06766.x.
ADP-induced and whole blood platelet adhesiveness have been studied by repeated measurements during the acute stage of the disease and the following two months in 86 randomly selected patients admitted to a coronary care unit because of acute central chest pain. In the patients who developed ECG and enzyme changes typical of infarction (group 1), platelet adhesiveness was significantly increased on admission compared with the rest of the patients (group 2) and controls (group 3). Patients in groups 1 and 2 showed a secondary increase during the first week, but two months after admission the means had returned to values within the normal range. No correlation was found between platelet adhesiveness and infarction size or fatal outcome of the disease. Platelet adhesiveness did not differ between patients with ECG changes indicating a transmural infarct and those with mainly subendocardial infarction.
对86例因急性胸痛入住冠心病监护病房的随机选取患者，在疾病急性期及随后两个月内通过重复测量研究了ADP诱导的全血血小板黏附性。在出现典型梗死心电图和酶变化的患者（第1组）中，入院时血小板黏附性与其余患者（第2组）及对照组（第3组）相比显著增加。第1组和第2组患者在第一周出现继发性增加，但入院两个月后均值已恢复至正常范围内的值。未发现血小板黏附性与梗死面积或疾病的致命结局之间存在相关性。心电图变化提示透壁梗死的患者与主要为心内膜下梗死的患者之间血小板黏附性无差异。
