单独吸入二氯甲烷以及与乙醇共同吸入对肝脏的影响。
Effects in the liver of methylene chloride inhaled alone and with ethyl alcohol.
作者信息
Balmer M F, Smith F A, Leach L J, Yuile C L
出版信息
Am Ind Hyg Assoc J. 1976 Jun;37(6):345-52. doi: 10.1080/0002889768507469.
PMID:937173
Abstract
When high concentrations of methylene chloride in combination with high concentrations of ethanol were inhaled for one day by guinea pigs, the extent of the hepatic damage induced suggested an antagonism between the effects of the two agents. However, exposure for five days to approximately 500 ppm of methylene chloride plus high concentrations of ethanol suggested ethanol may potentiate the effects of methylene chloride.
摘要
当豚鼠吸入高浓度二氯甲烷与高浓度乙醇的混合物一天时，所引发的肝脏损伤程度表明这两种药剂的作用之间存在拮抗作用。然而，暴露于约500 ppm的二氯甲烷加乙醇高浓度环境中五天后，表明乙醇可能会增强二氯甲烷的作用。
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