Riechmann J L, Meyerowitz E M
Division of Biology 156-29, California Institute of Technology, Pasadena 91125, USA.
Biol Chem. 1997 Oct;378(10):1079-101.
The MADS domain (MCM1, AGAMOUS, DEFICIENS, and SRF, serum response factor) is a conserved DNA-binding/dimerization region present in a variety of transcription factors from different kingdoms. MADS box genes represent a large multigene family in vascular plants. In angiosperms, many of the genes of the MADS family are involved in different steps of flower development, most notably in the determination of floral meristem and organ identity. The roles that MADS box genes play, however, are not restricted to control the development of the plant reproductive structures. The genetic, molecular, and biochemical basis of the action of the MADS domain proteins in the plant life cycle are reviewed here.
MADS结构域(MCM1、AGAMOUS、DEFICIENS和血清反应因子SRF)是一个保守的DNA结合/二聚化区域,存在于来自不同界的多种转录因子中。MADS盒基因在维管植物中代表一个庞大的多基因家族。在被子植物中,MADS家族的许多基因参与花发育的不同阶段,最显著的是在花分生组织和器官特性的决定方面。然而,MADS盒基因所起的作用并不局限于控制植物生殖结构的发育。本文综述了MADS结构域蛋白在植物生命周期中作用的遗传、分子和生化基础。