Greven C M, Wall A B
Wake Forest University Eye Center, Winston-Salem, NC 27157-1033, USA.
Am J Ophthalmol. 1997 Nov;124(5):687-9. doi: 10.1016/s0002-9394(14)70909-2.
To describe a patient with peripheral retinal neovascularization and vascular occlusion associated with activated protein C resistance.
Case report. A 63-year-old woman was examined for acute loss of vision in both eyes. She was noted to have macular edema in both eyes as well as a macular branch vein occlusion in the right eye and a central retinal vein occlusion in the left eye. Peripheral retinal neovascularization was present in both eyes.
Extensive systemic evaluation disclosed a heterozygous state for the factor V Leiden indicating activated protein C resistance.
Activated protein C resistance may be associated with peripheral retinal neovascularization.
描述一名患有外周视网膜新生血管形成及血管阻塞且与活化蛋白C抵抗相关的患者。
病例报告。一名63岁女性因双眼急性视力丧失接受检查。发现她双眼均有黄斑水肿,右眼有黄斑分支静脉阻塞,左眼有视网膜中央静脉阻塞。双眼均存在外周视网膜新生血管形成。
全面的系统评估显示该患者为因子V莱顿杂合状态,提示活化蛋白C抵抗。
活化蛋白C抵抗可能与外周视网膜新生血管形成有关。