Morales C, del Valle A, Rubio A, Mazón A, Rama J
Servicio de ORL, Hospital Sierrallana, Torrelavega.
Acta Otorrinolaringol Esp. 1997 May;48(4):295-8.
Three cases of laryngeal radionecrosis are reported. In two cases partial surgery after radiotherapy probably triggered the radionecrosis. All patients were treated successfully with medical therapy. Laryngeal radionecrosis is an uncommon complication of radiotherapy for carcinoma of the head and neck. The interval between conclusion of radiation therapy and development of radionecrosis ranges from 3 to 12 months. Neither computed tomography nor magnetic resonance imaging differentiate between necrotic tissue and recurrent tumor. Humidification, broad spectrum antibiotics, steroids, and hyperbaric oxygen, with or without surgery, are successful in many cases.
报告了3例喉放射性坏死病例。其中2例在放疗后进行的部分手术可能引发了放射性坏死。所有患者均通过药物治疗成功治愈。喉放射性坏死是头颈部癌放疗的一种罕见并发症。放疗结束至放射性坏死出现的间隔时间为3至12个月。计算机断层扫描和磁共振成像均无法区分坏死组织和复发性肿瘤。在许多情况下，加湿、广谱抗生素、类固醇和高压氧治疗，无论是否联合手术，都能取得成功。
