Hughes L E, Clifford C M, Gresbrink R, Thomas L A, Keirans J E
Am J Trop Med Hyg. 1976 May;25(3):513-6. doi: 10.4269/ajtmh.1976.25.513.
A rickettsia of the spotted fever group was isolated on three occasions from Ixodes pacificus in western Oregon. These isolations, and additional evidence furnished by complement fixation tests on guinea pigs inoculated with other Oregon ticks of this species, indicate that the association of this rickettsia with the Pacific Coast tick may be widespread. This is the first isolation of a spotted fever group rickettsia from I. pacificus. Because the Oregon isolates are mildly virulent for guinea pigs they resemble the Western U and Rickettsia montana strains of rickettsiae. However, preliminary evidence from cross-immunofluorescence tests of mouse antisera suggests the Tillamook and Grants Pass strains are antigenically different from all known spotted fever group agents.
在俄勒冈州西部，从太平洋硬蜱（Ixodes pacificus）中三次分离出斑点热群立克次体。这些分离结果，以及对接种了该物种其他俄勒冈蜱的豚鼠进行补体结合试验所提供的额外证据表明，这种立克次体与太平洋沿岸蜱的关联可能很普遍。这是首次从太平洋硬蜱中分离出斑点热群立克次体。由于俄勒冈分离株对豚鼠的毒性较弱，它们类似于立克次体的西部分支U株和蒙大拿立克次体菌株。然而，来自小鼠抗血清交叉免疫荧光试验的初步证据表明，蒂拉穆克（Tillamook）株和格兰茨帕斯（Grants Pass）株在抗原性上与所有已知的斑点热群病原体不同。
