Tardiff K, Marzuk P M, Leon A C, Hirsch C S, Portera L, Hartwell N
Department of Psychiatry, Cornell University Medical College, New York 10021, USA.
Addiction. 1997 Aug;92(8):1017-22.
To determine the factors associated with HIV seroprevalence rates for victims of drug overdoses.
Descriptive epidemiologic survey of a complete 3-year sample of accidental fatal drug overdoses.
New York City (population 7,322,564).
All people over 15 years of age (n = 2159) who died of accidental fatal drug overdoses during 1991-93.
Using medical examiner data and logistic regression analyses were conducted to examine the association between HIV seroprevalence and gender, race, age and type of drug overdose.
There were 646 (29.9%) victims who were HIV positive. Women (37.5%) were more likely than men (27.9%) to be HIV positive. African-Americans (39.4%) had a higher rate of HIV infection than Latinos (27.5%), whites (19.2%) or Asians (8.3%). Victims residing in communities with higher levels of poverty had higher rates of HIV infection but poverty did not account for the high rates of HIV infection among African-Americans. The highest rates of HIV infection were found among victims aged 35-44 years (38.8%) and 45-54 years (33.7%). Dying from an opiate overdose was associated with a 2.4 times increase in the likelihood of being HIV positive.
If opiate abuse continues to rise in the United States, HIV infection will increase in the next few years. Women who abuse drugs participate in risky sexual practices and are more likely than men to develop HIV infection from receptive sex as well as sharing of needles. Harm reduction programs should address risky sex as well as needle programs. There should be further study of why African-Americans who died of drug overdoses have the highest rates of HIV infection.
确定与药物过量受害者的艾滋病毒血清流行率相关的因素。
对3年期间所有意外致命药物过量案例进行描述性流行病学调查。
纽约市(人口7,322,564)。
1991年至1993年期间死于意外致命药物过量的所有15岁以上人群(n = 2159)。
利用法医数据并进行逻辑回归分析,以研究艾滋病毒血清流行率与性别、种族、年龄及药物过量类型之间的关联。
646名(29.9%)受害者艾滋病毒呈阳性。女性(37.5%)比男性(27.9%)更易艾滋病毒呈阳性。非裔美国人(39.4%)的艾滋病毒感染率高于拉丁裔(27.5%)、白人(19.2%)或亚裔(8.3%)。居住在贫困程度较高社区的受害者艾滋病毒感染率更高,但贫困并不能解释非裔美国人中艾滋病毒的高感染率。艾滋病毒感染率最高的是年龄在35 - 44岁(38.8%)和45 - 54岁(33.7%)的受害者。死于阿片类药物过量的人艾滋病毒呈阳性的可能性增加2.4倍。
如果美国阿片类药物滥用继续增加,未来几年艾滋病毒感染将会上升。滥用药物的女性会参与危险的性行为,并且比男性更易因接受性行为以及共用针头而感染艾滋病毒。减少伤害项目应同时关注危险性行为和针头项目。对于死于药物过量的非裔美国人艾滋病毒感染率最高的原因,应该进行进一步研究。