James L F, Van Kampen K R
Am J Vet Res. 1976 Jul;37(7):845-50.
Rats fed pellets containing locoweed developed typical microscopic lesions of locoweed poisoning. Rats fed a water extract of locoweed or urine from sheep given locoweed also developed microscopic lesions. This indicated that the locoweed toxin is water soluble and is excreted in the urine.