多西他赛使铂类难治性卵巢癌长期缓解：简要报告及文献综述

Prolonged remission of platinum-refractory ovarian cancer with docetaxel: brief report and review of literature.

作者信息

Balat O, Kudelka A P, Edwards C L, Verschraegen C F, Kavanagh J J

机构信息

University of Texas, M.D. Anderson Cancer Center, Houston, USA.

出版信息

Eur J Gynaecol Oncol. 1997;18(5):341-2.

PMID:9378149

Abstract

Platinum-based chemotherapy is the standard treatment for ovarian cancer, with response rates of 70-80%. Docetaxel has an increasing role as salvage therapy in patients with platinum-refractory ovarian cancer. In this report, we present the case of a patient with platinum-refractory ovarian cancer who achieved a long-term complete remission with docetaxel therapy. Two years after completion of chemotherapy with docetaxel, she continues to have no evidence of disease.

摘要

铂类化疗是卵巢癌的标准治疗方法，缓解率为70%-80%。多西他赛在铂耐药卵巢癌患者的挽救治疗中发挥着越来越重要的作用。在本报告中，我们介绍了一例铂耐药卵巢癌患者，该患者通过多西他赛治疗实现了长期完全缓解。在完成多西他赛化疗两年后，她仍然没有疾病迹象。