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[失代偿性糖尿病合并心肌梗死后的心衰。儿茶酚胺类药物的急性治疗——血管紧张素转换酶抑制剂与襻利尿剂联合的长期治疗]

[Heart failure after myocardial infarct in decompensated diabetes mellitus. Acute therapy with catecholamines--long-term therapy with ACE inhibitor-loop diuretic combination].

作者信息

Brilla C G

机构信息

Abteilung Kardiologie, Philipps-Universität Marburg.

出版信息

Fortschr Med. 1997 Aug 20;115(22-23):41-3.

PMID:9378433
Abstract

In a 63-year-old woman with longstanding type I diabetes mellitus, CAD and chronic heart failure, a subacute myocardial infarction developed, together with decompensation of cardiac function and diabetes and concurrent pneumonia. Acute heart failure with acute renal failure on top of diabetic nephropathy, and interstitial pulmonary edema was initially treated with hemofiltration and catechol amines together with antibiotic and perfusor-regulated insulin therapy, and systemic heparinization. Subsequent chronic treatment with digitalis, acetyl salicylic acid, insulin and a combination of an ACE inhibitor and a loop diuretic resulted in an improvement of heart failure to NYHA functional class II where PTCA of coronary multi-vessel disease could be performed with low risk.

摘要

一名63岁患有长期I型糖尿病、冠心病和慢性心力衰竭的女性,发生了亚急性心肌梗死,同时伴有心功能失代偿、糖尿病失代偿和并发肺炎。在糖尿病肾病基础上出现急性心力衰竭伴急性肾衰竭以及间质性肺水肿,最初采用血液滤过、儿茶酚胺类药物治疗,同时联合抗生素、灌注泵调节胰岛素治疗以及全身肝素化治疗。随后使用洋地黄、乙酰水杨酸、胰岛素以及血管紧张素转换酶抑制剂和袢利尿剂联合进行长期治疗,心力衰竭改善至纽约心脏协会(NYHA)心功能II级,在此情况下可低风险地进行冠状动脉多支病变的经皮冠状动脉腔内血管成形术(PTCA)。

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