牛唾液在伤口愈合中的治疗价值：一项组织形态学研究。

Therapeutic value of bovine saliva in wound healing: a histomorphological study.

作者信息

Varshney A C, Sharma D N, Singh M, Sharma S K, Nigam J M

机构信息

Department of Surgery and Radiology, College of Veterinary and Animal Sciences, H P Krishi Vishvavidyalaya, Palampur, India.

出版信息

Indian J Exp Biol. 1997 May;35(5):535-7.

PMID:9378522

Abstract

Biopsies were collected from the control (normal saline solution treated) and saliva treated wounds (back and loin region) of calves on 3rd, 7th, 14th, 21st and 28th days post-wounding. A faster connective tissue and epidermal regeneration was observed in saliva treated group. The inflammatory response was subdued as early as on 3rd day. On the 14th day the test wounds were covered with a dense layer of fibroblast and collagen and epidermal growth started. On 21st day the condensation of collagen and vascularization of the scar tissue was further augmented. By 28th day, the wounds were completely filled and nearly 85% of the wound surface was covered with epidermis.

摘要

在受伤后的第3天、第7天、第14天、第21天和第28天，从小牛的对照（用生理盐水处理）伤口和唾液处理伤口（背部和腰部区域）采集活检样本。在唾液处理组中观察到结缔组织和表皮再生更快。炎症反应早在第3天就得到抑制。在第14天，测试伤口覆盖有致密的成纤维细胞和胶原层，并且表皮开始生长。在第21天，瘢痕组织的胶原凝聚和血管化进一步增强。到第28天，伤口完全愈合，近85%的伤口表面被表皮覆盖。