Praschak-Rieder N, Neumeister A, Hesselmann B, Willeit M, Barnas C, Kasper S
Department of General Psychiatry, University of Vienna, Austria.
J Clin Psychiatry. 1997 Sep;58(9):389-92. doi: 10.4088/jcp.v58n0903.
Suicidality in seasonal affective disorder (SAD) subjects treated with bright light therapy seems to be a rare phenomenon. We report on three SAD patients with predominant atypical symptoms who presented for treatment in our clinic for SAD. Two suffered from bipolar disorder, one from recurrent major depressive disorder.
All subjects were drug-free and treated with bright light therapy as a monotherapy for the first time. Treatment response was assessed weekly by standardized rating instruments, using the Hamilton Rating Scale for Depression (HAM-D) and the HAM-D-SAD addendum for assessment of atypical symptoms.
Within the first week after beginning bright light therapy, two subjects attempted suicide. The third patient developed suicidal thoughts that were so acute and overwhelming that we had to discontinue bright light therapy and start with psychopharmacologic treatment in an inpatient setting.
It is suggested that bright light-induced amelioration of drive and mood can be dissociated as can be the case in the "critical time" of antidepressant therapy. The authors believe the collection of prevalence data on suicide and SAD would be worthwhile.
接受强光疗法治疗的季节性情感障碍(SAD)患者的自杀倾向似乎是一种罕见现象。我们报告了三名以非典型症状为主的SAD患者,他们在我们诊所接受SAD治疗。其中两名患有双相情感障碍,一名患有复发性重度抑郁症。
所有受试者均未服用药物,首次接受强光疗法单一治疗。每周使用标准化评分工具评估治疗反应,使用汉密尔顿抑郁量表(HAM-D)和用于评估非典型症状的HAM-D-SAD附录。
在开始强光疗法后的第一周内,两名受试者企图自杀。第三名患者出现的自杀念头非常强烈,以至于我们不得不停止强光疗法,并在住院环境中开始进行心理药物治疗。
有人认为,与抗抑郁治疗的“关键时期”情况一样,强光诱导的驱力和情绪改善可能会分离。作者认为收集自杀和SAD的患病率数据是值得的。