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New pancreatic lipases: gene expression, protein secretion, and the newborn.

作者信息

Lowe M E

机构信息

Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

出版信息

Methods Enzymol. 1997;284:285-97. doi: 10.1016/s0076-6879(97)84019-0.

DOI:10.1016/s0076-6879(97)84019-0
PMID:9379941
Abstract
摘要

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1
New pancreatic lipases: gene expression, protein secretion, and the newborn.
Methods Enzymol. 1997;284:285-97. doi: 10.1016/s0076-6879(97)84019-0.
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Bile salt-stimulated lipase and pancreatic lipase-related protein 2 are the dominating lipases in neonatal fat digestion in mice and rats.胆汁盐刺激脂肪酶和胰腺脂肪酶相关蛋白2是小鼠和大鼠新生儿脂肪消化中的主要脂肪酶。
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Sequence of horse pancreatic lipase as determined by protein and cDNA sequencing. Implications for p-nitrophenyl acetate hydrolysis by pancreatic lipases.
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Function, biosynthesis, secretion and intestinal degradation of a pancreatic hydrolase: the lipase of the rat exocrine pancreas.一种胰腺水解酶的功能、生物合成、分泌及肠道降解:大鼠外分泌胰腺的脂肪酶
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A structural domain (the lid) found in pancreatic lipases is absent in the guinea pig (phospho)lipase.豚鼠(磷酸)脂肪酶中不存在胰腺脂肪酶中发现的一种结构域(盖子)。
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引用本文的文献

1
Porcine pancreatic lipase related protein 2 has high triglyceride lipase activity in the absence of colipase.猪胰脂肪酶相关蛋白2在无辅脂酶的情况下具有高甘油三酯脂肪酶活性。
Biochim Biophys Acta. 2013 Sep;1831(9):1435-41. doi: 10.1016/j.bbalip.2013.06.002. Epub 2013 Jun 13.
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Development of the Digestive System-Experimental Challenges and Approaches of Infant Lipid Digestion.消化系统的发育——婴儿脂质消化的实验挑战与方法
Food Dig. 2012 Dec;3(1-3):63-77. doi: 10.1007/s13228-012-0025-x. Epub 2012 Nov 7.
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Pancreatic lipase-related protein-2 (PLRP2) can contribute to dietary fat digestion in human newborns.
胰腺脂肪酶相关蛋白-2(PLRP2)可促进人类新生儿对膳食脂肪的消化。
J Biol Chem. 2011 Jul 29;286(30):26353-63. doi: 10.1074/jbc.M111.249813. Epub 2011 Jun 7.
4
Kinetic properties of mouse pancreatic lipase-related protein-2 suggest the mouse may not model human fat digestion.鼠胰腺脂肪酶相关蛋白-2 的动力学特性表明,鼠可能不能模拟人体脂肪消化。
J Lipid Res. 2011 May;52(5):982-90. doi: 10.1194/jlr.M014290. Epub 2011 Mar 7.
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Decreased neonatal dietary fat absorption and T cell cytotoxicity in pancreatic lipase-related protein 2-deficient mice.胰腺脂肪酶相关蛋白2缺陷小鼠的新生小鼠膳食脂肪吸收减少及T细胞细胞毒性降低。
J Biol Chem. 1998 Nov 20;273(47):31215-21. doi: 10.1074/jbc.273.47.31215.