Pausch J, Wolfram H
Klinik und Poliklinik für Psychiatrie, Friedrich-Schiller-Universität, Jena.
Nervenarzt. 1997 Aug;68(8):638-46. doi: 10.1007/s001150050174.
Several cognitive impairment/dementia diagnostic methods were examined concerning their results: (a) in the differentiation of accidental and pathological ability changes; (b) in the demonstration/exclusion of cognitive impairment; and (c) the degree of dementia. Sixty-five patients suffering from brain damage were examined with five accepted methods of diagnosing dementia (Syndrom-kurztest, KAI-MWT-Methode, Demenz-Test, Mini-Mental-Status-Test, Wurzer-Methode) and a comprehensive performance test battery as an external criterion for valid determination of the degree of dementia and definite differentiation of accidental and pathological performance changes. The five methods of diagnosing dementia differ appreciably in determining the degree of severity (r = 0.44). They are effective in registering accidental performance changes in comparison with the outer criterion, but pathological changes are inaccurately registered (hit rate 88%/53%); the results concerning the degree of cognitive impairment are identical: between 25 and 43% (r = 0.43). High rates (58%) of false-negative diagnoses are especially apparent in the range of slight and intermediate cognitive impairment. The methods examined are only useful for the demonstration and not for the exclusion of severe cognitive impairment (dementia) and in no circumstances for the registration of slight/intermediate cognitive impairment. Valid diagnosis of cognitive impairment/dementia necessitates the use of test batteries that differentiate functions including the premorbid performance level.
对几种认知障碍/痴呆诊断方法的结果进行了研究:(a) 在区分偶然和病理性能力变化方面;(b) 在认知障碍的显示/排除方面;以及 (c) 痴呆程度方面。采用五种公认的痴呆诊断方法(综合征简短测试、KAI-MWT 方法、痴呆测试、简易精神状态测试、武泽方法)对 65 名脑损伤患者进行了检查,并使用一套综合性能测试作为有效确定痴呆程度以及明确区分偶然和病理性性能变化的外部标准。这五种痴呆诊断方法在确定严重程度方面有明显差异(r = 0.44)。与外部标准相比,它们在记录偶然性能变化方面有效,但病理性变化记录不准确(命中率 88%/53%);关于认知障碍程度的结果相同:在 25% 至 43% 之间(r = 0.43)。在轻度和中度认知障碍范围内,假阴性诊断的高比率(58%)尤为明显。所研究的方法仅有助于显示严重认知障碍(痴呆),而无助于排除,在任何情况下都无法记录轻度/中度认知障碍。认知障碍/痴呆的有效诊断需要使用能够区分包括病前表现水平在内的功能的测试组合。