Denbow M L, Sepulveda W, Ridout D, Fisk N M
Institute of Obstetrics and Gynaecology, Royal Postgraduate Medical School, Queen Charlotte's and Chelsea Hospital, London, United Kingdom.
Obstet Gynecol. 1997 Oct;90(4 Pt 1):529-32. doi: 10.1016/s0029-7844(97)00356-6.
To determine the relationship between the change in amniotic fluid index (AFI) and the volume of fluid removed at amnioreduction.
In a prospective study of 20 twin and 19 singleton pregnancies undergoing amnioreduction for severe polyhydramnios, AFI was measured immediately before and after the procedure and was correlated with the volume of fluid withdrawn.
A significant linear relationship was found between AFI change and the volume drained in all pregnancies (Y = -4.2X; R2 = 0.49; P = .002). This relationship was similar in singleton and twin pregnancies. However, there was a significant absolute difference in AFI change between singleton and twin pregnancies of 7.9 cm (95% confidence interval 0.41, 15.2; P = .04).
These findings support the use of the four-quadrant AFI as a semiquantitative index of amniotic fluid volume. This relationship can be used to predict the drainage volume required to achieve a target AFI with amnioreduction and thus avoid repeated AFI measurements during the procedure itself.
确定羊水指数（AFI）的变化与羊水减量术中抽出的羊水量之间的关系。
对20例双胎妊娠和19例单胎妊娠因严重羊水过多接受羊水减量术进行前瞻性研究，在手术前后即刻测量AFI，并将其与抽出的羊水量进行相关性分析。
在所有妊娠中，AFI变化与抽出的羊水量之间存在显著的线性关系（Y = -4.2X；R2 = 0.49；P = .002）。单胎妊娠和双胎妊娠中的这种关系相似。然而，单胎妊娠和双胎妊娠之间AFI变化的绝对差异显著，为7.9 cm（95%置信区间0.41，15.2；P = .04）。
这些发现支持将四象限AFI用作羊水量的半定量指标。这种关系可用于预测羊水减量术达到目标AFI所需的引流量，从而避免在手术过程中重复测量AFI。
