Coma-Canella I, García Velloso M J
Departamento de Cardiología y Cirugía Cardiovascular, Facultad de Medicina, Universidad de Navarra, Pamplona.
Rev Esp Cardiol. 1997 Sep;50(9):605-11. doi: 10.1016/s0300-8932(97)73272-x.
Positron emission tomography (PET) is a radionuclide imaging technique that allows quantitative assessment of regional myocardial function. It is mainly used in clinics to assess viability of dissynergic myocardium, by means of combined images of flow (with ammonia) and metabolism (with fluordeoxyglucose). The mismatch pattern, with an increase in fluordeoxyglucose metabolism in hypoperfused regions, is indicative of viability. The match pattern (a decrease in flow and metabolism in the same areas) is indicative of necrosis. Viability can also be assessed with water or fluordeoxyglucose independently quantified. Other promising methods are based in the study of oxygen consumption with 11C acetate and the study of hypoxia with 18F-misonidazole.
正电子发射断层扫描(PET)是一种放射性核素成像技术,可对局部心肌功能进行定量评估。它主要在临床上用于通过血流(用氨)和代谢(用氟脱氧葡萄糖)的联合图像来评估不同步心肌的存活能力。灌注不足区域的氟脱氧葡萄糖代谢增加的不匹配模式表明有存活能力。匹配模式(相同区域血流和代谢均降低)表明有坏死。也可以通过独立定量的水或氟脱氧葡萄糖来评估存活能力。其他有前景的方法基于用11C乙酸盐研究氧消耗以及用18F-米索硝唑研究缺氧情况。