Rygnestad T
Anestesiavdelingen Regionsykehuset i Trondheim.
Tidsskr Nor Laegeforen. 1997 Sep 10;117(21):3065-9.
The 15-year follow-up of mortality and the factors associated with death from various causes were studied in an unselected group of patients surviving deliberate self-poisoning in 1978. The cohort included 152 females and 101 males. By the end of 1993 a total of 37 (24%) of the females and 33 (33%) of the males admitted in 1978 had died. The total follow-up mortality was 4.5 times greater than expected for the female group (95% confidence interval: 3.1-6.1) and 3.6 times greater than expected (2.5-5.1) for the male group. It was highest in the first 5-year period. With regard to specific causes the mortality ratio was highest for deaths from suicide. For females it was 61.1 (30.5-109.4) and for males: 38.8 (20.4-65.4) times the expected ratio. It was also significantly raised for deaths from cardiovascular diseases in females: SMR = 3.7 (2.0-6.4) and from respiratory diseases in males: SMR = 3.3 (1.2-7.1). Significant predictors for death from all causes were age > or = 30 years: RR = 4.4 (2.3-8.5) and male sex: RR = 2.1 (1.2-3.5). Imprisonment was found to be a protective factor: RR = 0.2 (0.1-0.5). Predictors for death from suicide were age > or = 30: RR = 3.1 (1.2-8.1), male sex: RR = 3.3 (1.4-7.9) and a serious suicidal attempt, as evaluated by a psychiatrist: RR = 3.4 (1.4-7.9). It is concluded that patients who survive parasuicide by deliberate self-poisoning are at increased risk of death. The predictors for death are not very specific and are difficult to apply in clinical work with these patients.
对1978年因蓄意自我中毒而存活的一组未经挑选的患者进行了15年的死亡率随访以及与各种死因相关的因素研究。该队列包括152名女性和101名男性。到1993年底,1978年入院的女性中有37人(24%)死亡,男性中有33人(33%)死亡。女性组的总随访死亡率比预期高4.5倍(95%置信区间:3.1 - 6.1),男性组比预期高3.6倍(2.5 - 5.1)。在前5年期间死亡率最高。就具体死因而言,自杀死亡的死亡率比值最高。女性为61.1(30.5 - 109.4),男性为38.8(20.4 - 65.4)倍预期比值。女性心血管疾病死亡的死亡率也显著升高:标准化死亡比(SMR)= 3.7(2.0 - 6.4),男性呼吸系统疾病死亡的死亡率也显著升高:SMR = 3.3(1.2 - 7.1)。所有原因死亡的显著预测因素为年龄≥30岁:相对危险度(RR)= 4.4(2.3 - 8.5)以及男性性别:RR = 2.1(1.2 - 3.5)。发现监禁是一个保护因素:RR = 0.2(0.1 - 0.5)。自杀死亡的预测因素为年龄≥30岁:RR = 3.1(1.2 - 8.1),男性性别:RR = 3.3(1.4 - 7.9)以及经精神科医生评估为严重自杀未遂:RR = 3.4(1.4 - 7.9)。得出的结论是,因蓄意自我中毒而自杀未遂后存活的患者死亡风险增加。死亡的预测因素不是很特异,难以应用于对这些患者的临床工作中。