Hawton K, Harriss L, Zahl D
Centre for Suicide Research, University of Oxford Department of Psychiatry, Warneford Hospital, Oxford, UK.
Psychol Med. 2006 Mar;36(3):397-405. doi: 10.1017/S0033291705006914. Epub 2006 Jan 10.
Deliberate self-harm (DSH) may be associated with increased risk of death from a variety of causes, not just suicide.
A follow-up study of 11,583 DSH patients who presented to a general hospital over a 20-year period was conducted to examine risk of death from a range of causes during a follow-up period of between 3 and 23 years. Deaths were identified through national death registries. Expected numbers of deaths were calculated from national death statistics.
The number of deaths (1,185, 10.2%) was 2.2 times the expected number, the excess being significantly greater in males than females. Suicides were 17 times more frequent than expected and undetermined causes of death and accidental poisonings 15 times more frequent. Significantly more than expected numbers of deaths from most natural causes were found, including respiratory disease, circulatory, neurological, endocrine, digestive, skin and musculoskeletal and connective tissue disorders, and symptoms, signs and ill-defined conditions. Deaths due to accidents other than poisoning were more frequent than expected in both genders and homicides more frequent in males.
In addition to increased risk of suicide, DSH patients are at increased risk of dying from a wide range of other causes. Possible explanations include lifestyle factors, physical disorders contributing to initial risk of DSH, and social disadvantage. The findings are relevant to clinical management and evaluation of outcome and health-care costs associated with DSH.
蓄意自伤(DSH)可能与多种原因导致的死亡风险增加有关,而不仅仅是自杀。
对在20年期间到综合医院就诊的11583例DSH患者进行了一项随访研究,以检查在3至23年的随访期内各种原因导致的死亡风险。通过国家死亡登记处确定死亡情况。根据国家死亡统计数据计算预期死亡人数。
死亡人数(1185例,10.2%)是预期人数的2.2倍,男性的超额死亡人数明显多于女性。自杀发生率比预期高17倍,不明原因死亡和意外中毒发生率比预期高15倍。发现因大多数自然原因导致的死亡人数明显多于预期,包括呼吸系统疾病、循环系统、神经系统、内分泌系统、消化系统、皮肤和肌肉骨骼及结缔组织疾病,以及症状、体征和未明确诊断的疾病。除中毒外的事故导致的死亡在男女中均比预期更频繁,男性的凶杀案死亡比预期更频繁。
除了自杀风险增加外,DSH患者死于其他多种原因的风险也增加。可能的解释包括生活方式因素、导致DSH初始风险的身体疾病以及社会劣势。这些发现与DSH的临床管理、结局评估以及医疗保健成本相关。