de Korte C L, Céspedes E I, van der Steen A F, Norder B, te Nijenhuis K
Thoraxcentre, Erasmus University, The Netherlands Experimental Echocardiography, Rotterdam.
Ultrason Imaging. 1997 Apr;19(2):112-26. doi: 10.1177/016173469701900202.
The mechanical and acoustic properties of agar-gelatin gels, used to construct vessel mimicking phantoms for ultrasonic elasticity studies, were investigated. Gels with varying compression moduli were made using a gelatin solution (8% by weight) with a variable amount of agar (1%-3% by weight). Carborundum particles were added as scattering material. The compression modulus was determined using a dynamic mechanical analyzer. The dependence of the compression modulus and the acoustic parameters on the agar concentration, as well as on the age and the temperature of the samples, was investigated. The results show that the compression modulus is strongly influenced by these factors, while the effect on the acoustic parameters is less. Compression moduli spanning a useful range for vascular phantom construction with realistic acoustic parameters can be achieved by varying the amount of agar. Phantoms constructed from these gels are well suited to serve as a model for plaque containing vessels.
研究了用于构建用于超声弹性研究的血管模拟体模的琼脂 - 明胶凝胶的力学和声学特性。使用含有不同量琼脂(重量百分比为1%-3%)的明胶溶液(重量百分比为8%)制备具有不同压缩模量的凝胶。添加碳化硅颗粒作为散射材料。使用动态力学分析仪测定压缩模量。研究了压缩模量和声参数对琼脂浓度以及样品的老化和温度的依赖性。结果表明,这些因素对压缩模量有强烈影响,而对声学参数的影响较小。通过改变琼脂的量可以实现跨越适合构建具有实际声学参数的血管体模的有用范围的压缩模量。由这些凝胶构建的体模非常适合用作含斑块血管的模型。