Kolygin B A, Safonova S A, Malinin A P, Vesnin A G, Borodina A F, Punanov Iu A
Vopr Onkol. 1997;43(4):389-92.
A retrospective analysis of the results of treatment of 467 cases of primary Hodgkin's disease (aged under 15) (1968-1992) has been undertaken. As such invasive diagnostic procedures as lower direct lymphography and laparotomy with splenectomy were being abandoned, polychemotherapy plus irradiation of zones of involvement alone at all stages were introduced. Although generalized forms of tumor (stage III-IV tumors in 69% of cases) were in evidence and risk-adapted therapy procedures were used, the 5-year survival for 1988-1992 was 88%, the recurrence-free survival rate in the treated cases being 67%.
对467例原发性霍奇金病（年龄在15岁以下）（1968 - 1992年）的治疗结果进行了回顾性分析。随着诸如低位直接淋巴造影术和剖腹脾切除术等侵入性诊断程序被摒弃，引入了在所有阶段仅采用多药化疗加受累区域放疗的方法。尽管存在肿瘤的全身性形式（69%的病例为III - IV期肿瘤）且采用了风险适应性治疗程序，但1988 - 1992年的5年生存率为88%，接受治疗病例的无复发生存率为67%。
