Torta V, Smiroldo A F, Segatta P, Dvornik G, Vidi I
Unità Operativa di ORL, Ospedale S. Chiara, Trento.
Acta Otorhinolaryngol Ital. 1996 Dec;16(6):537-42.
Localized laryngeal amyloidosis is a rare laryngeal disease which accounts for less than 1% of all benign laryngeal tumors. The symptoms depend on where the amyloid deposit is located in the larynx. When the vocal cords are involved there may be some hoarseness; pain or increasing difficulty in inspiration may arise when, respectively, the aryepiglottic fold or subglottic space are involved. The present paper reports a case of laryngeal amyloidosis without any sign of systemic disease. It also deals with the principle diagnostic procedures to follow. After a review of the literature, emphasis is placed on how important it is to recognize laryngeal amyloidosis in order to achieve an appropriate diagnosis and plan therapy properly. Surgery is the main treatment using either endoscopy or an external neck approach. Recently CO2 laser surgery has been used successfully. Prognosis depends on both the size of the amyloid deposit and whether there is some simultaneous overall involvement.
局限性喉淀粉样变是一种罕见的喉部疾病,占所有良性喉部肿瘤的比例不到1%。症状取决于淀粉样沉积物在喉部的位置。当声带受累时,可能会出现声音嘶哑;当杓会厌襞或声门下间隙受累时,分别可能会出现疼痛或吸气困难加重。本文报告一例无任何全身疾病迹象的喉淀粉样变病例。还讨论了应遵循的主要诊断程序。在回顾文献后,强调了认识喉淀粉样变对于做出正确诊断和合理规划治疗的重要性。手术是主要治疗方法,可采用内镜手术或颈部外入路。最近,二氧化碳激光手术已成功应用。预后取决于淀粉样沉积物的大小以及是否同时存在全身受累情况。