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[将吸气最初100毫秒时的阻断压(P0.1)作为急性呼吸衰竭中降低呼吸支持可能性的指标]

[Occlusion pressure in the first 100 ms of inspiration (P0.1) as an index of the possibility of decreasing respiratory support in acute respiratory failure].

作者信息

Neverin V K, Marchenkov Iu V

出版信息

Anesteziol Reanimatol. 1997 Jul-Aug(4):40-5.

PMID:9382227
Abstract

The need in making the process of transfer of patients to spontaneous respiration using ventilation of the lungs with inspiratory pressure support (VLIPS) after prolonged mechanical ventilation of the lungs prompted the authors to analyze the prognostic value of criteria traditionally used by the physician to cease or decrease the respiratory support (vital capacity of the lungs, peak spontaneous flow, PaO2, etc.) and the P0.1 occlusion pressure in the airways at the end of the first 100 msec of inhalation. This latter value proved to be the most sensitive (88%), specific (86%), positive (95%) and negative (67%) prognostic value in predicting the results of decrease of respiratory support under conditions of VLIPS. The P0.1 value determining the result of decrease of respiratory support in patients with parenchymatous pulmonary diseases under conditions of VLIPS is 3.8 cm H2O.

摘要

在长时间肺机械通气后,采用吸气压力支持肺通气(VLIPS)使患者转为自主呼吸的过程中的需求,促使作者分析医生传统上用于停止或减少呼吸支持的标准(肺肺活量、自主呼吸峰值流量、动脉血氧分压等)以及吸气开始后最初100毫秒末气道内的P0.1阻断压的预后价值。结果证明,在预测VLIPS条件下呼吸支持减少的结果时,后一数值具有最高的敏感性(88%)、特异性(86%)、阳性预测值(95%)和阴性预测值(67%)。在VLIPS条件下,决定实质性肺部疾病患者呼吸支持减少结果的P0.1值为3.8厘米水柱。

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