细胞因子信号传导：细胞因子诱导的信号传导抑制剂

Cytokine signaling: cytokine-inducible signaling inhibitors.

作者信息

Aman M J, Leonard W J

机构信息

Laboratory of Molecular Immunology, National Institute of Health, National Heart, Lung, and Blood Institute, Bethesda, Maryland 20893, USA.

出版信息

Curr Biol. 1997 Dec 1;7(12):R784-8. doi: 10.1016/s0960-9822(06)00405-2.

DOI:10.1016/s0960-9822(06)00405-2

PMID:9382832

Abstract

Seven members of a family of cytokine-inducible proteins have been identified, a number of which have been shown to act as negative regulators of cytokine action. All of these proteins contain a central Src homology 2 domain, as well as conserved motifs in their carboxy-terminal regions.

摘要

已鉴定出细胞因子诱导蛋白家族的七个成员，其中一些已被证明可作为细胞因子作用的负调节因子。所有这些蛋白都含有一个中央Src同源2结构域，以及其羧基末端区域的保守基序。