Aman M J, Leonard W J
Laboratory of Molecular Immunology, National Institute of Health, National Heart, Lung, and Blood Institute, Bethesda, Maryland 20893, USA.
Curr Biol. 1997 Dec 1;7(12):R784-8. doi: 10.1016/s0960-9822(06)00405-2.
Seven members of a family of cytokine-inducible proteins have been identified, a number of which have been shown to act as negative regulators of cytokine action. All of these proteins contain a central Src homology 2 domain, as well as conserved motifs in their carboxy-terminal regions.
已鉴定出细胞因子诱导蛋白家族的七个成员，其中一些已被证明可作为细胞因子作用的负调节因子。所有这些蛋白都含有一个中央Src同源2结构域，以及其羧基末端区域的保守基序。
