羊瘙痒病感染的化学原理：“冰九”隐喻的启示
The chemistry of scrapie infection: implications of the 'ice 9' metaphor.
作者信息
Lansbury P T, Caughey B
机构信息
Department of Chemistry, Massachusetts Institute of Technology, Cambridge, USA.
出版信息
Chem Biol. 1995 Jan;2(1):1-5. doi: 10.1016/1074-5521(95)90074-8.
PMID:9383397
Abstract
The transmissible spongiform encephalopathies pose an increasing problem for animal, and perhaps human, health. The infectious agent seems to lack a nucleic acid component, posing the question of how it can reproduce. A model of reproduction by nucleated polymerization suggests a number of novel approaches to the problem.
摘要
传染性海绵状脑病对动物乃至人类健康构成了日益严重的问题。这种传染因子似乎缺乏核酸成分，这就引发了它如何进行繁殖的问题。一种通过有核聚合进行繁殖的模型为解决该问题提供了一些新方法。
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