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新城疫的气溶胶疫苗接种。II. 疫苗稀释剂的作用。

Aerosol vaccination against Newcastle disease. II. Effect of vaccine diluents.

作者信息

Villegas P, Kleven S H

出版信息

Avian Dis. 1976 Apr-Jun;20(2):260-7.

PMID:938375
Abstract

Three diluents (deionized water, 2% dry milk, and 20% buffered glycerin) were used to suspend the Newcastle disease vaccine for aerosol-vaccination studies. Particle size and the effect on humoral antibody response in chickens was determined for each diluent. For all diluents, the greatest number of particles were found in the size range of 0.5-3 mum. Total particle counts were higher with glycerin than with either milk or water. Antibody response and resistance to challenge, however, were higher with water or milk.

摘要

使用三种稀释剂(去离子水、2%干奶和20%缓冲甘油)来悬浮新城疫疫苗,用于气溶胶疫苗接种研究。测定了每种稀释剂的粒径及其对鸡体液抗体反应的影响。对于所有稀释剂,在0.5-3微米的粒径范围内发现的颗粒数量最多。甘油的总颗粒计数高于牛奶或水。然而,水或牛奶的抗体反应和攻毒抗性更高。

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