Witz C A, Schenken R S
Department of Obstetrics and Gynecology, University of Texas Health Science Center at San Antonio 78284, USA.
Semin Reprod Endocrinol. 1997;15(3):199-208. doi: 10.1055/s-2008-1068749.
There are many hypotheses concerning the pathogenesis of endometriosis, though no single theory can explain all cases. It is likely that several mechanisms are involved. Early studies concentrated on the histogenesis of the endometriotic lesion. Recent evidence has implicated components of the immune system in the pathogenesis of endometriosis. This review considers the evidence for different theories of the histogenesis of endometriosis and discusses possible immune factors that may be involved in the pathophysiology of the disease.
关于子宫内膜异位症的发病机制有许多假说,尽管没有单一理论能够解释所有病例。很可能涉及多种机制。早期研究集中在子宫内膜异位病变的组织发生上。最近的证据表明免疫系统的成分与子宫内膜异位症的发病机制有关。这篇综述考虑了关于子宫内膜异位症组织发生的不同理论的证据,并讨论了可能参与该疾病病理生理学的免疫因素。