Tamura M, Zama A, Kurihara H, Kano T, Imai H, Ishiuchi S, Iwai T, Naito I
Department of Neurosurgery, Gunma University School of Medicine, Maebashi, Japan.
Brain Tumor Pathol. 1997;14(1):35-9. doi: 10.1007/BF02478866.
The clinical and histological characteristics of oligodendroglioma and oligoastrocytoma were investigated in patients, mainly adults with supratentorial tumors, who were treated with surgery and radiotherapy, and with chemotherapy for recurrent, anaplastic tumors, or both. The median survival time was 13.2 years for oligodendroglioma (four patients), 12.7 years for anaplastic oligodendroglioma (five patients), 13.5 years for oligoastrocytoma (seven patients), and 4.8 years for anaplastic oligoastrocytoma (four patients). Two of three recurrent oligodendrogliomas and two of two recurrent oligoastrocytomas showed malignant transformation. Minigemistocytes were sometimes recognized in recurrent tumors and had a sinister prognosis. Oligodendroglioma and oligoastrocytoma may transform into each other at recurrence.
对少突胶质细胞瘤和少突星形细胞瘤的临床及组织学特征进行了研究，研究对象主要是患有幕上肿瘤的成年人，这些患者接受了手术和放疗，对于复发的间变性肿瘤或两者皆有的情况还接受了化疗。少突胶质细胞瘤（4例患者）的中位生存时间为13.2年，间变性少突胶质细胞瘤（5例患者）为12.7年，少突星形细胞瘤（7例患者）为13.5年，间变性少突星形细胞瘤（4例患者）为4.8年。3例复发性少突胶质细胞瘤中的2例以及2例复发性少突星形细胞瘤中的2例出现了恶性转化。在复发性肿瘤中有时可识别出微小神经胶质细胞，其预后不佳。少突胶质细胞瘤和少突星形细胞瘤在复发时可能会相互转化。
Zotero 插件