Noda S, Sundt T M, Lynch J P, Trulock E P, Sundaresan S, Patterson G A
Department of Surgery, Washington University School of Medicine, St. Louis, Missouri 63110, USA.
Ann Thorac Surg. 1997 Nov;64(5):1459-61. doi: 10.1016/S0003-4975(97)00942-9.
Single-lung transplantation for pulmonary hypertension results in a significant ventilation/perfusion mismatch with dramatic shift of blood flow, but not ventilation, to the replacement organ. This raises concern that the patient may be precariously dependent on the function of the transplanted lung. We report the successful management of a massive central pulmonary embolus to the transplanted lung in a 43-year-old woman 4 years after single-lung transplantation for primary pulmonary hypertension.
用于治疗肺动脉高压的单肺移植会导致显著的通气/灌注不匹配，血流会戏剧性地转向移植肺，而通气情况并非如此。这引发了人们对患者可能严重依赖移植肺功能的担忧。我们报告了一名43岁女性在因原发性肺动脉高压接受单肺移植4年后，成功处理了移植肺发生的巨大中央型肺栓塞的病例。
