Cai G, Yu Y, Ma Z
Zhong Shan Hospital, Shanghai Medical University.
Zhonghua Zhong Liu Za Zhi. 1996 May;18(3):218-20.
Eleven patients with hepatic metastases from colorectal cancer survived more than 5 years after the resection were reviewed. There were 3 (27.3%) disease-free survivors, the longest survival period was 7 years and 2 months. Compared with 41 survivors of less than 5-year duration after resection, it was shown that close follow-up after resection of the primary cancer, detecting early subclinical hepatic metastases, preoperative lower level of CEA, tumor less or equal to 5 cm in size, single metastatic nodule and radical resection were important factors influening long-term survival (P < 0.05). It is of the opinion that early diagnosis, early resection and re-resection after detecting subclinical local recurrence and metastases play important role in improving long-term response.
回顾了11例结直肠癌肝转移患者,他们在肝转移灶切除术后存活超过5年。其中有3例(27.3%)无病生存者,最长生存期为7年2个月。与41例切除术后生存期不足5年的幸存者相比,结果显示,原发癌切除术后密切随访、早期发现亚临床肝转移、术前CEA水平较低、肿瘤大小小于或等于5 cm、单个转移结节以及根治性切除是影响长期生存的重要因素(P<0.05)。认为早期诊断、早期切除以及在发现亚临床局部复发和转移后再次切除对提高长期疗效起重要作用。