Li F, Zheng X, Qu L
Third Affiliated Hospital of Harbin Medical University.
Zhonghua Zhong Liu Za Zhi. 1996 Nov;18(6):455-7.
In order to differentiate benign from malignant pulmonary masses by means of observing blood flow signal, with coloured Doppler sonography, the authors examined 67 in-patients who had been found having masses in the lungs by X-ray or CT. For comparison 43 benign cases showing blood signals in the lung was also examined. The results showed that the blood flow signals of all lung cancers were of relatively low blood flow resistance or arteriovenous shunting, while those of benign lesions were of high blood flow resistance. The pulsatility index in lung cancer was 1.02 +/- 0.30, the restance index was 0.52 +/- 0.13, the peak systolic velocity was 0.19 +/- 0.11 m/s, the end diastolic velocity was 0.06 +/- 0.02 m/s. The pulsatility index in benign pulmonary lesions was 1.53 +/- 0.30, the resitance index was 0.86 +/- 0.05, the peak systolic velocity was 0.28 +/- 0.05 m/s and the end diastolic velocity was 0.04 +/- 0.01 m/s. There were significant differences between the benign and malignant pulmonary lesions in the four indices (P < 0.01) by t test and t' test. Lower pulsatility index, lower resistance index, lower peak systolic velocity and higher end diastolic velocity were characteristics of malignancy.
为了通过观察血流信号,运用彩色多普勒超声来鉴别肺部肿块的良恶性,作者对67例经X线或CT检查发现肺部有肿块的住院患者进行了检查。作为对照,还检查了43例肺部显示有血流信号的良性病例。结果显示,所有肺癌的血流信号均表现为相对较低的血流阻力或动静脉分流,而良性病变的血流信号则为高血流阻力。肺癌的搏动指数为1.02±0.30,阻力指数为0.52±0.13,收缩期峰值流速为0.19±0.11m/s,舒张末期流速为0.06±0.02m/s。良性肺部病变的搏动指数为1.53±0.30,阻力指数为0.86±0.05,收缩期峰值流速为0.28±0.05m/s,舒张末期流速为0.04±0.01m/s。经t检验和t'检验,这四个指标在良性和恶性肺部病变之间存在显著差异(P<0.01)。搏动指数降低、阻力指数降低、收缩期峰值流速降低和舒张末期流速升高是恶性病变的特征。