Wright A K, Baxter J E
Biophys J. 1976 Aug;16(8):931-8. doi: 10.1016/S0006-3495(76)85743-8.
An iterative numerical technique is presented which allows the semiaxes for prolate and oblate ellipsoids to be determined from the Perrin equations for rotational and translational diffusion constants. The use of this inversion technique is illustrated by application to the proteins: lysozyme, bovine serum albumin, human transferrin, and bovine rhodopsin solubilized in digitonin.
本文提出了一种迭代数值技术,该技术可根据旋转和平移扩散常数的佩兰方程确定长椭球体和扁椭球体的半轴。通过将该反演技术应用于溶解在洋地黄皂苷中的溶菌酶、牛血清白蛋白、人转铁蛋白和牛视紫红质等蛋白质,说明了该技术的应用。