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23例经尸检证实的肺栓塞临床病理研究

[Clinical pathological study on 23 pulmonary embolism proved by autopsy].

作者信息

Sun T, Miao J, Zhang Z

机构信息

Department of Pulmonology, Beijing Hospital.

出版信息

Zhonghua Jie He He Hu Xi Za Zhi. 1996 Jun;19(3):152-4.

PMID:9387485
Abstract

OBJECTIVE

To improve the early diagnosis of pulmonary embolism.

METHODS

The clinical and pathological data of 23 cases of autopsy-proved pulmonary embolism in Beijing hospital from 1951 to 1994 were reviewed.

RESULTS

23 patients: male 18, female 5, age ranged from 34 to 82 years. Misdiagnosis rate was 87%. The unexplained dyspnea, chest pain, sudden onset dyspnea and sudden death were the most frequent symptoms. Arterial blood gas data frequently demonstrated hypoxia and hypocapnia. The most important causes of an incorrect diagnosis could be the failure of suspecting pulmonary embolism, because of the variability of clinical manifestation and the presence of other concomitant diseases.

CONCLUSION

All patients with otherwise severe unexplained dyspnea or chest pain have to be sent for perfusion lung scintigraphy, accordingly, underdetection of pulmonary embolism and mortality of pulmonary embolism could be reduced.

摘要

目的

提高肺栓塞的早期诊断率。

方法

回顾性分析1951年至1994年北京医院23例经尸检证实的肺栓塞患者的临床及病理资料。

结果

23例患者中,男性18例,女性5例,年龄34至82岁。误诊率为87%。不明原因的呼吸困难、胸痛、突发呼吸困难和猝死是最常见的症状。动脉血气分析常显示低氧血症和低碳酸血症。误诊的最重要原因可能是由于临床表现的多样性和其他伴随疾病的存在而未能怀疑肺栓塞。

结论

所有有严重不明原因呼吸困难或胸痛的患者都应进行肺灌注闪烁扫描,从而可减少肺栓塞的漏诊率和死亡率。

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