[抗毒生血汤对辐射损伤小鼠脾和胸腺恢复作用的组织病理学研究]

[A histopathologic study on recovering effect of kangdu shengxue decoction on spleen and thymus of mice with radiation injury].

作者信息

Wang L Y, Wu Z Y, Zhang X Y

机构信息

Department of Pathology, Guanganmen Hospital, China Academy of Traditional Chinese Medicine, Beijing.

出版信息

Zhongguo Zhong Xi Yi Jie He Za Zhi. 1996 Aug;16(8):489-91.

PMID:9387752

Abstract

The effect of Kangdu Shengxue Decoction (KDSXD) on the spleen and thymus of mice irradiated with 80Co gamma-rays has been studied by histopathological methods. 130 LACA mice were divided into 3 groups. Control and experimental groups were generally irradiated for once with 8 Gy 80Co gamma-rays. The experiment of group were treated with KDSXD one hour before irradiation and consecutively five days after radiation. The results of experiment showed that 30 days after irradiation the structure of spleen and thymus of treated mice normalized. The difference of recovery between control and experimental group showed a high significance statistically (P < 0.01).

摘要

采用组织病理学方法研究了抗毒生血汤（KDSXD）对80Coγ射线照射小鼠脾脏和胸腺的影响。将130只LACA小鼠分为3组。对照组和实验组均一次性接受8 Gy 80Coγ射线全身照射。实验组在照射前1小时用抗毒生血汤治疗，并在照射后连续治疗5天。实验结果表明，照射后30天，治疗组小鼠的脾脏和胸腺结构恢复正常。对照组与实验组恢复情况的差异具有高度统计学意义（P < 0.01）。