Cox D P, Goldsmith C D
Appl Environ Microbiol. 1979 Sep;38(3):514-20. doi: 10.1128/aem.38.3.514-520.1979.
A culture of Nocardia tartaricans ATCC 31190 was capable of catalyzing the conversion of ethylbenzene to 1-phenethanol and acetophenone while growing in a shake flask culture with hexadecane as the source of carbon and energy. This subterminal oxidative reaction with ethylbenzene appears not to have been previously reported for Nocardia species. When N. tartaricans was grown on glucose as its source of carbon and energy and ethylbenzene was added, no subsequent production of 1-phenethanol or acetophenone was observed. The mechanisms of 1-phenethanol and acetophenone production from ethylbenzene are thought to involve a subterminal oxidation of the alpha-carbon of the alkyl group to 1-phenethanol followed by biological oxidation of the latter to acetophenone.
在以十六烷作为碳源和能源的摇瓶培养中生长时,龋齿诺卡氏菌ATCC 31190的培养物能够催化乙苯转化为1-苯乙醇和苯乙酮。这种与乙苯的亚末端氧化反应似乎此前尚未见诺卡氏菌属的相关报道。当龋齿诺卡氏菌以葡萄糖作为碳源和能源进行培养并添加乙苯时,未观察到随后有1-苯乙醇或苯乙酮的产生。由乙苯生成1-苯乙醇和苯乙酮的机制被认为涉及烷基α-碳的亚末端氧化生成1-苯乙醇,随后后者再进行生物氧化生成苯乙酮。