Man A, Schwarz Y, Greif J
Department of Allergy and Pulmonary Diseases, Tel-Aviv Sourasky Medical Centre, Israel.
Eur Respir J. 1997 Oct;10(10):2425-6. doi: 10.1183/09031936.97.10102425.
Pharmacological ovarian stimulation is an accepted technique for amplifying the normal process of follicular development and maturation. It has been in use for the past decade, especially in cases of infertility. Pleural effusion associated with ovarian hyperstimulation syndrome (OHSS), a complication of this therapy, may be more prevalent than is commonly accepted. Four young women presented to our department with dyspnoea caused by pleural effusion as a result of ovarian hyperstimulation syndrome (OHSS). The diagnosis of OHSS was based on a history of pharmacological ovarian stimulation, clinical and laboratory evidence of ovarian enlargement and exclusion of other potential causes of pleural effusion in young women, such as infections, malignancy, pulmonary embolism and collagen vascular diseases. The fluid characteristics in all cases were exudative, with low to normal LDH. All of these patients required fluid evacuation for symptomatic relief. Resolution was achieved with supportive measures and rest. Ovarian hyperstimulation syndrome may be common enough to warrant routine consideration in the differential diagnosis of pleural effusion in young women.
药物性卵巢刺激是一种用于放大卵泡发育和成熟正常过程的公认技术。在过去十年中一直在使用，尤其是在不孕症病例中。与卵巢过度刺激综合征（OHSS）相关的胸腔积液是这种治疗的一种并发症，可能比普遍认为的更为普遍。四名年轻女性因卵巢过度刺激综合征（OHSS）导致的胸腔积液前来我院就诊，出现呼吸困难。OHSS的诊断基于药物性卵巢刺激史、卵巢肿大的临床和实验室证据以及排除年轻女性胸腔积液的其他潜在原因，如感染、恶性肿瘤、肺栓塞和胶原血管疾病。所有病例的液体特征均为渗出液，乳酸脱氢酶水平低至正常。所有这些患者都需要进行液体引流以缓解症状。通过支持性措施和休息实现了缓解。卵巢过度刺激综合征可能很常见，在年轻女性胸腔积液的鉴别诊断中值得常规考虑。
