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Capsaicin stimulates release of substance P from dorsal root ganglion neurons via two distinct mechanisms.

作者信息

Purkiss J R, Welch M J, Doward S, Foster K A

机构信息

CAMR (Centre of Applied Microbiology and Research), Salisbury, Wiltshire, U.K.

出版信息

Biochem Soc Trans. 1997 Aug;25(3):542S. doi: 10.1042/bst025542s.

DOI:10.1042/bst025542s
PMID:9388756
Abstract
摘要

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1
Capsaicin stimulates release of substance P from dorsal root ganglion neurons via two distinct mechanisms.
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Capsaicin-stimulated release of substance P from cultured dorsal root ganglion neurons: involvement of two distinct mechanisms.
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Substance P release evoked by capsaicin or potassium from rat cultured dorsal root ganglion neurons is conversely modulated with bradykinin.辣椒素或钾离子诱发的大鼠培养背根神经节神经元中P物质的释放与缓激肽呈反向调节。
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Activated eosinophils elicit substance P release from cultured dorsal root ganglion neurons.
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Olopatadine attenuates the enhancement of capsaicin-evoked substance P release by bradykinin from cultured dorsal root ganglion neurons.奥洛他定可减弱缓激肽对培养的背根神经节神经元中辣椒素诱发的P物质释放的增强作用。
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Regulatory effect of nerve growth factor on release of substance P in cultured dorsal root ganglion neurons of rat.神经生长因子对大鼠背根神经节培养神经元中P物质释放的调节作用
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The release of substance P from cultured dorsal root ganglion neurons requires the non-neuronal cells around these neurons.培养的背根神经节神经元中P物质的释放需要这些神经元周围的非神经元细胞。
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Butyrate sensitizes the release of substance P and calcitonin gene-related peptide evoked by capsaicin from primary cultured rat dorsal root ganglion neurons.丁酸盐可增强辣椒素诱导的原代培养大鼠背根神经节神经元中P物质和降钙素基因相关肽的释放。
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Biglycan Inhibits Capsaicin-Induced Substance P Release by Cultured Dorsal Root Ganglion Neurons.双糖链蛋白聚糖抑制辣椒素诱导培养的背根神经节神经元释放P物质。
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Ca(2+)-dependent exocytosis in the somata of dorsal root ganglion neurons.背根神经节神经元胞体中依赖钙离子的胞吐作用。
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