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妊娠高血压综合征中医辨证的临床研究

A clinical study on TCM differentiation of symptoms and signs in pregnancy hypertension syndrome.

作者信息

Jin Y, Sha W, Gao X, Li E

机构信息

Beijing Obstetrical and Gynecological Hospital.

出版信息

J Tradit Chin Med. 1996 Dec;16(4):252-9.

PMID:9389097
Abstract

An epidemiological investigation was made into the diagnostic types of 457 cases of pregnancy classified according to differentiation of symptoms and signs by traditional Chinese medicine (TCM) with the aim of finding out its relationship with pregnancy hypertension syndrome (PHS). The total occurrence rate of PHS was 36.8%. In early pregnancy, 65.9% of patients with deficiency of yin of the liver had a high rate of developing PHS, while in the intermediate stage, 61.6% of patients with deficiency of the spleen and exuberance of the liver were most liable to develop it. In 50 cases diagnosed and treated on the basis of TCM differentiation of symptoms and signs the incidence was reduced to be 20%. The changes of such biochemical indices as ACh, AChE, cholic acid and gastrin in different diagnostic types during pregnancy, as well as the effect of spleen-invigorating therapy on these indices in pregnancy with deficiency of the spleen were also observed.

摘要

对457例按中医症状体征辨证分型的妊娠病例进行了流行病学调查,旨在找出其与妊娠高血压综合征(PHS)的关系。PHS的总发生率为36.8%。妊娠早期,肝阴虚患者中65.9%发生PHS的几率较高,而妊娠中期,脾虚肝旺患者中61.6%最易发生PHS。在50例按中医症状体征辨证论治的病例中,发病率降至20%。还观察了妊娠不同诊断类型中乙酰胆碱(ACh)、乙酰胆碱酯酶(AChE)、胆酸和胃泌素等生化指标的变化,以及健脾疗法对脾虚妊娠患者这些指标的影响。

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Uncovering the Pharmacological Mechanism of Astragalus Salvia Compound on Pregnancy-Induced Hypertension Syndrome by a Network Pharmacology Approach.基于网络药理学方法揭示黄芪丹参复方治疗妊娠高血压综合征的药理机制。
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