弗氏完全佐剂致人体意外伤害9例报告
Report of nine cases of accidental injury to man with Freund's complete adjuvant.
作者信息
Chapel H M, August P J
出版信息
Clin Exp Immunol. 1976 Jun;24(3):538-41.
Abstract
Nine cases of accidental injury with Freund's complete adjuvant to man are reported. One case is reported in detail and the other eight have been seen and reviewed retrospectively. Reactions developed in Mantoux positive individuals, who injected Freund's complete adjuvant with another protein. However, not all such injections produced the reaction. Treatment was unsuccessful, although one reaction may have been aborted by early surgical excision of the site of injection.
摘要
报告了9例人因弗氏完全佐剂导致意外伤害的病例。详细报告了1例，其余8例进行了回顾性观察和复查。反应发生在向已接种过结核菌素试验呈阳性的个体注射弗氏完全佐剂与另一种蛋白质的过程中。然而，并非所有此类注射都会引发反应。尽管有1例反应可能因早期手术切除注射部位而得到缓解，但治疗并不成功。
相似文献
1
Report of nine cases of accidental injury to man with Freund's complete adjuvant.弗氏完全佐剂致人体意外伤害9例报告
Clin Exp Immunol. 1976 Jun;24(3):538-41.
2
Accidental self-injection with Freund's complete adjuvant.意外自我注射弗氏完全佐剂。
J Assoc Physicians India. 2001 Mar;49:366-8.
3
Accidental self injection with Freund's complete adjuvant.意外自我注射弗氏完全佐剂。
J Assoc Physicians India. 2002 May;50(5):742; author reply 742.
4
Accidental injection of Freund's adjuvant with minimal reaction.意外注射弗氏佐剂，反应轻微。
Lancet. 1979 Aug 25;2(8139):424-5. doi: 10.1016/s0140-6736(79)90445-8.
5
Immunologic responses and adverse reactions to Freund's-adjuvanted porcine zona pellucida immuno-contraceptives in domestic cats.家猫对弗氏佐剂猪透明带免疫避孕药的免疫反应和不良反应。
Vaccine. 2005 Dec 1;23(48-49):5646-54. doi: 10.1016/j.vaccine.2005.05.044. Epub 2005 Aug 18.
6
Accidental injection of Freund's adjuvant without systemic sequelae.意外注射弗氏佐剂且无全身后遗症。
Lancet. 1979 Aug 18;2(8138):356. doi: 10.1016/s0140-6736(79)90364-7.
7
Comparison of immune and adverse effects induced by AdjuVac and Freund's complete adjuvant in New Zealand white rabbits (Oryctolagus cuniculus).AdjuVac与弗氏完全佐剂对新西兰白兔（穴兔）诱导的免疫和不良反应比较。
Lab Anim (NY). 2007 Oct;36(9):51-8. doi: 10.1038/laban1007-51.
8
An evaluation of distress following intraperitoneal immunization with Freund's adjuvant in mice.小鼠腹腔注射弗氏佐剂后应激反应的评估。
Lab Anim Sci. 1989 Mar;39(2):122-6.
9
Tuberculosis-like lesions arising from the use of Freund's complete adjuvant in an owl monkey (Aotus sp.).一只夜猴（夜猴属）因使用弗氏完全佐剂而出现的结核样病变。
J Med Primatol. 2004 Apr;33(2):109-12. doi: 10.1111/j.1600-0684.2004.00060.x.
10
Lesions in sheep following administration of a vaccine of a Freund's complete adjuvant nature used in the control of ovine paratuberculosis.在使用具有弗氏完全佐剂性质的疫苗控制绵羊副结核病后绵羊出现的病变。
N Z Vet J. 2006 Oct;54(5):237-41. doi: 10.1080/00480169.2006.36704.
引用本文的文献
1
Formulation of an ovarian cancer vaccine with the squalene-based AddaVax adjuvant inhibits the growth of murine epithelial ovarian carcinomas.含角鲨烯佐剂AddaVax的卵巢癌疫苗制剂可抑制小鼠上皮性卵巢癌的生长。
Clin Exp Vaccine Res. 2022 May;11(2):163-172. doi: 10.7774/cevr.2022.11.2.163. Epub 2022 May 31.
2
Nanoemulsions: Formulation, characterization, biological fate, and potential role against COVID-19 and other viral outbreaks.纳米乳剂：配方、表征、生物学命运以及对 COVID-19 和其他病毒爆发的潜在作用。
Colloid Interface Sci Commun. 2021 Nov;45:100533. doi: 10.1016/j.colcom.2021.100533. Epub 2021 Oct 20.
3
Glucan particles as a novel adjuvant for the induction of experimental autoimmune encephalomyelitis.葡聚糖颗粒作为一种新型佐剂诱导实验性自身免疫性脑脊髓炎。
Cell Immunol. 2021 Aug;366:104383. doi: 10.1016/j.cellimm.2021.104383. Epub 2021 May 21.
4
GM-CSF-loaded chitosan hydrogel as an immunoadjuvant enhances antigen-specific immune responses with reduced toxicity.负载粒细胞-巨噬细胞集落刺激因子的壳聚糖水凝胶作为免疫佐剂可增强抗原特异性免疫反应并降低毒性。
BMC Immunol. 2014 Oct 18;15:48. doi: 10.1186/s12865-014-0048-x.
5
Intramuscular injection of antigens and adjuvant preferentially decreases 18:2n-6 and 18:3n-3 in pig neck muscle.肌肉注射抗原和佐剂会优先降低猪颈部肌肉中的18:2n-6和18:3n-3。
Lipids. 2003 Dec;38(12):1221-6. doi: 10.1007/s11745-003-1182-x.
本文引用的文献
1
Autogenous vaccine in cancer patients.癌症患者的自体疫苗。
Surg Gynecol Obstet. 1962 Jan;114:1-4.
2
Studies in tumor autoimmunity.肿瘤自身免疫研究。
Cancer Res. 1960 Apr;20:351-6.
3
A study in clinical cancer immunotherapy.一项临床癌症免疫疗法研究。
Cancer. 1970 Aug;26(2):269-78. doi: 10.1002/1097-0142(197008)26:2<269::aid-cncr2820260205>3.0.co;2-x.
4
Koch's phenomenon involving the flexor tendon sheath. Adjuvant-induced tenosynovitis in man.涉及屈肌腱鞘的科赫现象。佐剂诱导的人类腱鞘炎。
J Bone Joint Surg Am. 1969 Oct;51(7):1413-9. doi: 10.2106/00004623-196951070-00020.
5
Letter: B.C.G. and immunological anergy.信件：卡介苗与免疫无反应性。
Lancet. 1974 May 18;1(7864):989-90. doi: 10.1016/s0140-6736(74)91296-3.
6
Letter: Clindamycin and pseudomembranous colitis.信件：克林霉素与伪膜性结肠炎。
Lancet. 1974 Jan 12;1(7846):66. doi: 10.1016/s0140-6736(74)93067-0.
7
Letter: Accidental injection of Freund's adjuvant.信函：意外注射弗氏佐剂。
Lancet. 1975 Apr 12;1(7911):863-4. doi: 10.1016/s0140-6736(75)93047-0.
Zotero 插件