Bakshi N, Maselli R A, Gospe S M, Ellis W G, McDonald C, Mandler R N
Department of Neurology, University of California-Davis, 95616, USA.
Muscle Nerve. 1997 Dec;20(12):1595-7. doi: 10.1002/(sici)1097-4598(199712)20:12<1595::aid-mus17>3.0.co;2-#.
Guillain-Barré syndrome can very rarely present with acute quadripares and cranial nerve involvement resembling a locked-in state. We describe a very unusual case of fulminant neuropathy in a child who was previously exposed to vincristine. The clinical picture resembled brain death; however, electrodiagnostic studies led to the diagnosis of a peripheral neuropathy. Serial electrodiagnostic studies and pathologic findings confirmed demyelination.
格林-巴利综合征极少会表现为急性四肢瘫和颅神经受累，类似闭锁综合征。我们描述了一例非常罕见的暴发性神经病患儿病例，该患儿此前曾接触过长春新碱。临床表现类似脑死亡；然而，电诊断研究最终确诊为周围神经病。系列电诊断研究和病理结果证实存在脱髓鞘改变。
