Lantieri L A, Roudot-Thoraval F, Collins E D, Raulo Y, Baruch J P
Department of Plastic Surgery, Henri Mondor Hospital, Paris XII University, Creteil, France.
Plast Reconstr Surg. 1997 Dec;100(7):1740-4; discussion 1745. doi: 10.1097/00006534-199712000-00015.
The authors report a series of 407 patients with a total of 709 saline breast implants (average follow-up, 7.1 years). In this retrospective series, the overall deflation rate was 6.6 percent (47 of 709). Initial comparison of the deflation rates for smooth (8.8 percent) versus textured (1.8 percent) implants suggested a significant difference between the implant types. However, further analysis of the data revealed that smooth implants had a longer average follow-up period and tended to have lower fill volumes. These data were re-examined using Kaplan-Meier survival analysis plots, which corrected for differences in follow-up times, and log rank tests performed to determine significance. Implant type was found to have a non-significant association with rupture rate. In contrast, the percent fill (implant fill volume per minimum recommended fill volume x 100) was significantly associated with the spontaneous ruptures; a mean difference of 13.9 percent (89.2 percent versus 103.1 percent) was found between the series of deflated implants and the nondeflated implants (p < 0.0001). These data suggest that underfilling is a major cause of deflation.
作者报告了一组407例患者，共植入709个盐水乳房植入物（平均随访7.1年）。在这个回顾性系列研究中，总体瘪陷率为6.6%（709个中有47个）。对光面植入物（8.8%）与毛面植入物（1.8%）的瘪陷率进行初步比较，结果提示植入物类型之间存在显著差异。然而，对数据的进一步分析显示，光面植入物的平均随访期更长，且填充量往往更低。使用Kaplan-Meier生存分析图重新审视这些数据，该分析图校正了随访时间的差异，并进行对数秩检验以确定其显著性。结果发现植入物类型与破裂率之间无显著关联。相比之下，填充百分比（植入物填充量占最低推荐填充量的百分比×100）与自发性破裂显著相关；在瘪陷的植入物系列和未瘪陷的植入物系列之间，发现平均差异为13.9%（89.2%对103.1%）（p<0.0001）。这些数据表明填充不足是瘪陷的主要原因。
