Bhagia S M, Elek E M, Grimer R J, Carter S R, Tillman R M
Royal Orthopaedic Hospital, Birmingham, England, UK.
J Bone Joint Surg Br. 1997 Nov;79(6):924-6. doi: 10.1302/0301-620x.79b6.7770.
We reviewed 20 patients after forequarter amputation performed for high-grade malignant tumours of the shoulder girdle (Enneking grades IIB to III). The operations were classified as palliative or curative according to the resection margins and the presence of disseminated disease at the time of the surgery. There were five palliative and 15 curative procedures. Two patients died from unrelated causes, septicaemia and suicide. Eight died in the first two years, four of whom had had a palliative operation. Four died between two and five years after surgery, one after a palliative operation. Five patients are alive, at a mean of 89.4 months after surgery, four of whom are free from disease. The median survival after a palliative amputation was 20.6 months. Our overall five-year survival (palliative and curative cases) was 21.2%, for curative cases it was 30.2%. None of the patients use an artificial prosthesis. Despite the disfigurement which results from this operation, it still has a useful role to play in the management of high-grade malignant tumours of the upper limb.
我们回顾了20例因肩胛带高度恶性肿瘤(Enneking分期IIB至III期)而接受前半侧截肢术的患者。根据手术切缘以及手术时是否存在播散性疾病,将手术分为姑息性或根治性。其中有5例姑息性手术和15例根治性手术。两名患者死于败血症和自杀等非相关原因。8例在头两年内死亡,其中4例接受了姑息性手术。4例在术后两年至五年间死亡,其中1例接受了姑息性手术。5例患者存活,术后平均存活89.4个月,其中4例无疾病。姑息性截肢术后的中位生存期为20.6个月。我们总的五年生存率(姑息性和根治性病例)为21.2%,根治性病例为30.2%。所有患者均未使用人工假体。尽管该手术会导致身体外形受损,但它在上肢高度恶性肿瘤的治疗中仍发挥着有益作用。