生物组织和类组织体模的时间选通透照与反射的计算机模拟。

Computer simulation of time-gated transillumination and reflection of biological tissues and tissuelike phantoms.

作者信息

Michielsen K, De Raedt H, García N

机构信息

Institute for Theoretical Physics and Materials Science Centre, University of Groningen, The Netherlands.

出版信息

Med Phys. 1997 Nov;24(11):1688-95. doi: 10.1118/1.597955.

DOI:10.1118/1.597955

PMID:9394275

Abstract

A simulation technique is employed to explore the possibility of locating millimeter-sized objects, immersed in turbid media, from time-gated measurements of the transmitted or reflected light. The simulation results for tissuelike phantoms are compared to experimental transillumination data and excellent agreement is found. Simulations of time-gated reflection experiments show that it is possible to detect objects of 1 mm diameter. This may open new possibilities for medical diagnosis of breast cancer in an early stage.

摘要

采用一种模拟技术，通过对透射光或反射光进行时间选通测量，来探索定位浸没在混浊介质中的毫米级物体的可能性。将组织样体模的模拟结果与实验透照数据进行比较，发现二者吻合良好。时间选通反射实验的模拟结果表明，有可能检测到直径为1毫米的物体。这可能为乳腺癌的早期医学诊断开辟新的途径。