Mathews K G, Gregory C R
Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis 95616-8734, USA.
J Am Vet Med Assoc. 1997 Dec 1;211(11):1432-6.
To document the morbidity and survival time after renal transplants in cats with end-stage renal failure.
Retrospective case series.
66 cats that had renal transplants.
Information regarding signalment, history, diagnostic testing, and postoperative morbidity and mortality was retrieved from medical records of cats with renal failure that had renal transplants at the University of California School of Veterinary Medicine between 1987 and 1996.
47 of 66 (71%) cats that had renal transplants survived until discharge. Nineteen cats died in the perioperative period. Most common causes of death were seizure-related complications (7 cats) and renal pedicle complications (4). One discharged cat was unavailable for follow-up monitoring. Of the 46 cats discharged and available for follow-up monitoring, 28 died. Most common causes of death in these cats were renal complications (9 cats) and death related to immunosuppression (8; mean and median survival times, 15 and 12 months, respectively). Of the 18 cats that were still living at the time this report was written, mean and median survival times were 26 and 22 months, respectively.
Renal transplantation resulted in long-term survival of many cats that would have otherwise died from, or have been euthanatized as a result of, renal failure. Problems with ureteral obstruction can be minimized. Postoperative CNS disorders were the most prevalent complication.
记录终末期肾衰竭猫肾移植后的发病率和存活时间。
回顾性病例系列研究。
66只接受肾移植的猫。
从1987年至1996年在加利福尼亚大学兽医学院接受肾移植的肾衰竭猫的病历中获取有关体征、病史、诊断检查以及术后发病率和死亡率的信息。
66只接受肾移植的猫中有47只（71%）存活至出院。19只猫在围手术期死亡。最常见的死亡原因是癫痫相关并发症（7只猫）和肾蒂并发症（4只）。1只出院的猫无法进行随访监测。在46只出院且可进行随访监测的猫中，28只死亡。这些猫最常见的死亡原因是肾脏并发症（9只猫）和与免疫抑制相关的死亡（8只；平均和中位存活时间分别为15个月和12个月）。在撰写本报告时仍存活的18只猫中，平均和中位存活时间分别为26个月和22个月。
肾移植使许多原本会因肾衰竭死亡或被安乐死的猫获得了长期存活。输尿管梗阻问题可降至最低。术后中枢神经系统疾病是最常见的并发症。
