Tripodi S A, Laurini L, Presenti L, Brunettini C, Boncompagni G, Messina M, D'Agata A, Del Vecchio M T
Department of Pathology, University of Siena.
Minerva Urol Nefrol. 1997 Sep;49(3):169-71.
Villous adenomas of the bladder are rare tumors and up to now they have not been seen to undergo malignant transformation. We report a case of villous adenoma of the bladder with areas of adenocarcinoma in a 72-year-old man. We describe all the morphological, histochemical and immunohistochemical features characterizing this tumor. We recommend adequate pathological sampling and a thorough follow-up of patients with villous adenoma. The prognosis and the behaviour of these adenomatous papillary lesions, morphologically similar to colonic adenomas, in the bladder is unclear. We report a case with focal area of adenocarcinoma and review the literature.
膀胱绒毛状腺瘤是罕见肿瘤,迄今为止尚未见其发生恶变。我们报告一例72岁男性膀胱绒毛状腺瘤伴腺癌区域的病例。我们描述了该肿瘤的所有形态学、组织化学和免疫组织化学特征。我们建议对绒毛状腺瘤患者进行充分的病理取样和全面随访。这些腺瘤性乳头状病变在形态上与结肠腺瘤相似,其在膀胱中的预后和行为尚不清楚。我们报告一例伴有腺癌局灶区域的病例并复习文献。