Kitaoka Y
Department of Obstetrics and Gynecology, Kyoto National Hospital.
Nihon Rinsho. 1997 Nov;55(11):3012-9.
Polycystic Ovary Syndrome(PCOS) was originally reported by Stein and Leventhal in 1935, as an syndrome with bilateral polycystic ovaries, menstrual abnormality, hirsutism and obesity etc. After this report the diagnosis of "Polycystic Ovary" was abused for the patient only with polycystic change of ovaries, so that, the concept or definition of PCOS has became unclear and controversial. In this review, a classification of PCOS according to the presence of hyperandrogenemia and/or hirsutism will be shown to reconstruct the concept or definition of PCOS. And usefulness of this classification will be revealed by showing endocrinological and morphological aspect of each class. Furthermore, new therapeutic approaches for PCOS with pure FSH injection in combination with GnRH analog against the onset of OHSS, or drillings of antral follicles with CO2 or KTP laser will be also shown in this review.
多囊卵巢综合征（PCOS）最初由斯坦因（Stein）和莱文索尔（Leventhal）于1935年报道，是一种具有双侧多囊卵巢、月经异常、多毛和肥胖等症状的综合征。在此报道之后，“多囊卵巢”的诊断被滥用于仅具有卵巢多囊性改变的患者，以至于PCOS的概念或定义变得不明确且存在争议。在本综述中，将展示一种根据高雄激素血症和/或多毛症的存在情况对PCOS进行的分类，以重构PCOS的概念或定义。并且通过展示每一类的内分泌和形态学方面来揭示这种分类的实用性。此外，本综述还将展示针对PCOS的新治疗方法，即单纯注射促卵泡生成素（FSH）联合促性腺激素释放激素（GnRH）类似物以防止卵巢过度刺激综合征（OHSS）的发生，或使用二氧化碳或磷酸钛钾（KTP）激光对窦卵泡进行打孔。
