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Reversal of syphilitic hydrocephalus with intravenous penicillin.

作者信息

Cosottini M, Mascalchi M, Zaccara G, Arnetoli G

机构信息

Clinica Neurologica II, Università di Firenze, Florence, Italy.

出版信息

Can J Neurol Sci. 1997 Nov;24(4):343-4. doi: 10.1017/s0317167100033035.

DOI:10.1017/s0317167100033035
PMID:9398983
Abstract

BACKGROUND

CSF shunting procedures are generally considered the fundamental therapy of syphilitic hydrocephalus.

METHODS

We followed up with CSF analysis and MR imaging a patient with progressive mental and gait disturbances and tetraventricular hydrocephalus due to tertiary syphilis who was treated for 14 days with high dose intravenous penicillin alone.

RESULTS

Clinical and CSF abnormalities resolved within a few months, whereas the hydrocephalus disappeared only 30 months after therapy.

CONCLUSIONS

Before consideration of a CSF shunting procedure, a trial of high dose intravenous penicillin is warranted for patients with syphilitic hydrocephalus.

摘要

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